disorder of plasmalogens biosynthesis
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MONDO_0017986 |
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disorder of peroxisomal transporter defect
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MONDO_0100372 |
[Any peroxisomal single enzyme/protein defect that disrupts peroxisomal transport.] |
disorder of peroxisomal beta oxidation
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MONDO_0019233 |
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distal renal tubular acidosis
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MONDO_0015827 |
[Distal renal tubular acidosis (dRTA) is a disorder of impaired net acid secretion by the distal tubule characterized by hyperchloremic metabolic acidosis. The classic form is often associated with hypokalemia whereas other forms of acquired dRTA may be associated with hypokalemia, hyperkalemia or normokalemia.] |
kidney disorder
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MONDO_0005240 |
[A disease involving the kidney.] |
Ehlers-Danlos syndrome, cardiac valvular type
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MONDO_0009159 |
[Ehlers-Danlos syndrome, cardiac valvular type is a form of Ehlers-Danlos syndrome characterized by soft skin, skin hyperextensibility, easy bruisability, atrophic scar formation, joint hypermobility and cardiac valvular defects comprising mitral and/or aortic valve insufficiency.] |
heart disorder
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MONDO_0005267 |
[A disease involving the heart and/or pericardium.] |
Ehlers-Danlos syndrome
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MONDO_0020066 |
[The Ehlers–Danlos syndromes (EDS) are a clinically and genetically heterogeneous group of heritable connective tissue disorders (HCTDs) characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.] |
EEM syndrome
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MONDO_0009155 |
[EEM syndrome is characterized by the association of ectodermal dysplasia, ectrodactyly, and macular dystrophy. So far, it has been described in individuals from seven families. Hypotrichosis, dental anomalies and absent eyebrows have also been reported. EMM syndrome appears to be transmitted as an autosomal recessive trait and may be caused by mutations in the cadherin-3 gene (CH3, 16q22.1).] |
hereditary macular dystrophy
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MONDO_0020242 |
[Macular dystrophy that is related to a change in a gene.] |
Brugada syndrome 1
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MONDO_0011001 |
[Any Brugada syndrome in which the cause of the disease is a mutation in the SCN5A gene.] |
Brugada syndrome
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MONDO_0015263 |
[A genetically heterogeneous condition characterized by complete or incomplete right bundle branch block accompanied by ST elevation in leads V1-V3. There is a high incidence of ventricular arrhythmia that may result in sudden death.] |
rhizomelic chondrodysplasia punctata type 4
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MONDO_0014510 |
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eye disorder
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MONDO_0005328 |
[A non-neoplastic or neoplastic disorder that affects the eye. Representative examples include conjunctivitis, glaucoma, cataract, conjunctival squamous cell carcinoma, uveal melanoma, and retinoblastoma.] |
chondrodysplasia punctata
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MONDO_0019701 |
[A rare congenital developmental disorder characterized by the presence of stippled foci of calcification in the hyaline cartilage, joint contractions, mental retardation and ichthyosis.] |
fatty acyl-CoA reductase defects
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MONDO_0100275 |
[Any disorder of plasmalogen biosynthesis in which the cause of the disease is a mutation in the FAR1 gene.] |
Troyer syndrome
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MONDO_0010156 |
[Autosomal recessive spastic paraplegia type 20 (SPG20) is a type of complex hereditary spastic paraplegia characterized by an onset in infancy of progressive spastic paraparesis associated with distal amyotrophy, psuedobulbar palsy, motor and cognitive delays, mild cerebellar signs (dysarthria, dysdiadochokinesia, mild intention tremor), short stature and subtle skeletal abnormalities (pes cavus, mild talipes equinovarus, kyphoscoliosis). SPG20 is due to mutations in the SPG20 gene (13q13.1), which encodes the protein spartin.] |
Dorfman-Chanarin disease
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MONDO_0010155 |
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neutral lipid storage disease
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MONDO_0015611 |
[Neutral lipid storage disease (NLSD) refers to a group of diseases characterized by a deficit in the degradation of cytoplasmic triglycerides and their accumulation in cytoplasmic lipid vacuoles in most tissues of the body. The group is heterogeneous: currently cases of NLSD with icthyosis (NLSDI/Dorfman-Chanarin disease) and NLSD with myopathy (NLSDM/neutral lipid storage myopathy) can be distinguished.] |
myofibrillar myopathy 8
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MONDO_0014993 |
[Any myofibrillar myopathy in which the cause of the disease is a mutation in the PYROXD1 gene.] |