A degenerative disease of the brain that causes gradual loss of memory, judgment, and the ability to function socially. About 25% of all Alzheimer disease is familial (more than 2 people in a family have AD). When Alzheimer disease begins before 60 or 65 years of age (early-onset AD) about 60% of the cases are familial (also known as Early-onset familial AD). These cases appear to be inherited in an autosomal dominant manner. [ GARD:0000632 ]
Synonyms: FAD Alzheimer disease, familial GARD:0000632
Term information
- UMLS:C0276496 (MONDO:equivalentTo)
- MEDGEN:82914 (MONDO:equivalentTo)
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