Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation. [ MESH:D002275 ]
Synonyms: carcinoid heart disease
Term information
- UMLS:C0007093 (MONDO:equivalentTo)
- SCTID:36222008 (MONDO:equivalentTo)
- MESH:D002275 (MONDO:equivalentTo)
- MEDGEN:762 (MONDO:equivalentTo)
http://identifiers.org/mesh/D002275
http://linkedlifedata.com/resource/umls/id/C0007093
http://identifiers.org/medgen/762
http://identifiers.org/snomedct/36222008