Wolfram-like syndrome is a rare endocrine disease characterized by the triad of adult-onset diabetes mellitus, progressive hearing loss (usually presenting in the first decade of life and principally of low to moderate frequencies), and/or juvenile-onset optic atrophy. Psychiatric (i.e. anxiety, depression, hallucinations) and sleep disorders, the only neurologic abnormalities observed in this disease, have been reported in rare cases. Unlike Wolfram syndrome, patients with Wolfram-like syndrome do not report endocrine or cardiac findings. [ Orphanet:411590 ]
Synonyms: Wolfram-like syndrome
Term information
- MEDGEN:481988 (MONDO:equivalentTo)
- SCTID:734022008 (MONDO:equivalentTo)
- UMLS:C3280358 (MONDO:equivalentTo)
- GARD:17683 (MONDO:GARD)
- Orphanet:411590 (OMIM:614296)
- OMIM:614296 (Orphanet:411590/e)
- MESH:C565631 (MONDO:equivalentTo)
- DOID:0080584 (MONDO:equivalentTo)
gard_rare, ordo_disorder, rare, nord_rare, orphanet_rare, clingen
http://purl.obolibrary.org/obo/DOID_0080584
http://linkedlifedata.com/resource/umls/id/C3280358
http://identifiers.org/snomedct/734022008
https://omim.org/entry/614296
http://www.orpha.net/ORDO/Orphanet_411590
http://identifiers.org/medgen/481988
http://identifiers.org/mesh/C565631
WFSL
Wolfram-like syndrome, autosomal dominant
hearing loss, progressive, with optic atrophy and/or impaired glucose Regulation