transient myeloproliferative syndrome
Go to external page http://purl.obolibrary.org/obo/MONDO_0008040
A myeloid proliferation occurring in newborns with Down syndrome. It is clinically and morphologically indistinguishable from acute myeloid leukemia and is associated with GATA1 mutations. The blasts display morphologic and immunophenotypic features of megakaryocytic lineage. In the majority of patients the myeloid proliferation undergoes spontaneous remission. [ NCIT:P378 ]
Synonyms: transient myeloproliferative syndrome (disease) TAM transient leukaemia transient myeloproliferative disease TMD leukemia, transient, of Down syndrome MST transient leukemia transient myeloproliferative disorder transient myeloproliferative syndrome transient abnormal myelopoiesis transient leurkemia of Down syndrome Transient abnormal myelopoiesis associated with Down syndrome
Term information
- HP:0005534 (MONDO:otherHierarchy)
- SCTID:721307000 (MONDO:equivalentTo)
- Orphanet:420611 (OMIM:159595)
- ICDO:9898/1 (NCIT:C82339)
- NCIT:C82339 (MONDO:equivalentTo)
- GARD:12765 (MONDO:GARD)
- OMIM:159595 (Orphanet:420611/e)
- MEDGEN:331782 (MONDO:equivalentTo)
- ONCOTREE:TAM (MONDO:equivalentTo)
- DOID:0060888 (MONDO:equivalentTo)
- MESH:C563551 (MONDO:equivalentTo)
- UMLS:C1834582 (MONDO:equivalentTo)
gard_rare, ordo_disorder, rare, nord_rare, orphanet_rare
http://purl.obolibrary.org/obo/NCIT_C82339
https://omim.org/entry/159595
http://purl.obolibrary.org/obo/DOID_0060888
http://identifiers.org/medgen/331782
http://www.orpha.net/ORDO/Orphanet_420611
http://linkedlifedata.com/resource/umls/id/C1834582
http://identifiers.org/snomedct/721307000
http://identifiers.org/mesh/C563551