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hepatocellular carcinoma

Go to external page http://purl.obolibrary.org/obo/MONDO_0007256

A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation. [ NCIT:C3099 ]

Synonyms: hepatocellular cancer, somatic hepatoblastoma, somatic hepatocellular adenocarcinoma hepatoma HCC primary carcinoma of the liver cells primary carcinoma of liver cells carcinoma of liver cancer, hepatocellular liver cell carcinoma liver cell cancer (hepatocellular carcinoma) carcinoma of liver cells liver carcinoma hepatocellular carcinoma, childhood type, somatic carcinoma of the liver cells hepatocellular carcinoma, somatic hepatocellular cancer hepatocellular carcinoma carcinoma, hepatocellular, malignant

This is just here as a test because I lose it

Term information

database cross reference
  • icd11.foundation:1294035808 (https://orcid.org/0000-0001-5208-3432)
  • NORD:1907 (MONDO:NORD)
  • MESH:D006528 (Orphanet:88673/e)
  • NCIT:C3099 (MONDO:equivalentTo)
  • MEDGEN:389187 (MONDO:equivalentTo)
  • ONCOTREE:HCC (MONDO:equivalentTo)
  • Orphanet:88673 (OMIM:114550)
  • GARD:16773 (MONDO:GARD)
  • DOID:684 (MONDO:equivalentTo)
  • EFO:0000182 (MONDO:equivalentTo)
  • NANDO:2200047 (https://orcid.org/0000-0003-0011-764X)
  • DOID:686 (MONDO:equivalentTo)
  • OMIM:114550 (Orphanet:88673/e)
  • ICDO:8170/3 (NCIT:C3099)
  • UMLS:C2239176 (MONDO:equivalentTo)
  • MedDRA:10049010 (Orphanet:88673/e)
Subsets

gard_rare, otar, rare, nord_rare, ordo_group_of_disorders

abbreviation
HCC [ https://omim.org/entry/114550 Orphanet:88673 NCIT:C3099 DOID:684 ]

closeMatch

http://identifiers.org/meddra/10049010

exactMatch

http://purl.obolibrary.org/obo/NCIT_C3099

https://omim.org/entry/114550

http://purl.obolibrary.org/obo/DOID_686

http://purl.obolibrary.org/obo/DOID_684

http://identifiers.org/medgen/389187

http://linkedlifedata.com/resource/umls/id/C2239176

http://identifiers.org/mesh/D006528

http://www.orpha.net/ORDO/Orphanet_88673

has narrow synonym

adult primary hepatocellular carcinoma

adult hepatoma

has related synonym

hepatoblastoma

liver and intrahepatic bile duct carcinoma

hepatoblastoma caused by somatic mutation

liver cancer

id

MONDO:0007256

term tracker item

https://github.com/monarch-initiative/mondo/issues/4521