A slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement. [ NCIT:C2915 ]
Synonyms: NET G1 carcinoid tumor neuroendocrine tumor G1 neuroendocrine neoplasm G1 carcinoid tumour (disease) carcinoid neuroendocrine tumour G1 carcinoid tumor (disease)
Term information
- UMLS:C0007095 (MONDO:equivalentTo)
- MESH:D002276 (MONDO:equivalentTo)
- ICDO:8241/3 (NCIT:C2915)
- NANDO:2200396 (https://orcid.org/0000-0003-0011-764X)
- HP:0100570 (MONDO:otherHierarchy)
- ICD9:209.60 (MONDO:i2s)
- ICDO:8240/3 (NCIT:C2915)
- NCIT:C2915 (MONDO:equivalentTo)
- SCTID:443492008 (MONDO:equivalentTo)
- MEDGEN:2838 (MONDO:equivalentTo)
- EFO:0004243 (MONDO:equivalentTo)
gard_rare, otar, rare
Editor note: In NCIT all carcinoid tumors are grade 1, but the name is sometimes used more broadly in other sources
http://linkedlifedata.com/resource/umls/id/C0007095
http://purl.obolibrary.org/obo/NCIT_C2915
http://identifiers.org/medgen/2838
http://identifiers.org/snomedct/443492008
http://identifiers.org/mesh/D002276