A squamous cell carcinoma arising from the oral cavity. It affects predominantly adults in their fifth and sixth decades of life and is associated with alcohol and tobacco use. Human papillomavirus is present in approximately half of the cases. It is characterized by a tendency to metastasize early to the lymph nodes. When the tumor is small, patients are often asymptomatic. Physical examination may reveal erythematous or white lesions or plaques. The majority of patients present with signs and symptoms of locally advanced disease including mucosal ulceration, pain, difficulty with speaking, chewing, and swallowing, bleeding, weight loss, and neck swelling. Patients may also present with swollen neck lymph nodes without any symptoms from the oropharyngeal tumor. The most significant prognostic factors are the size of the tumor and the lymph nodes status. [ NCIT:C4833 ]

Synonyms: mouth scc squamous cell carcinoma of mouth oral cavity squamous cell cancer scc of the mouth squamous cell carcinoma of oral cavity scc of mouth squamous cell carcinoma of the oral cavity oral cavity scc mouth squamous cell carcinoma squamous cell carcinoma of the mouth scc of the oral cavity oral cavity squamous cell carcinoma scc of oral cavity

This is just here as a test because I lose it

Term information

database cross reference
  • GARD:17932 (MONDO:GARD)
  • EFO:0000199 (MONDO:equivalentTo)
  • Orphanet:502363 (MONDO:equivalentTo)
  • UMLS:C0585362 (MONDO:equivalentTo)
  • SCTID:307502000 (MONDO:equivalentTo)
  • MEDGEN:108436 (MONDO:equivalentTo)
  • DOID:0050866 (MONDO:equivalentTo)
  • ONCOTREE:OCSC (MONDO:equivalentTo)
  • NCIT:C4833 (MONDO:equivalentTo)
Subsets

ordo_disorder, gard_rare, otar, rare, nord_rare, orphanet_rare

abbreviation
OCSC [ ONCOTREE:OCSC ]

conformsTo

http://purl.obolibrary.org/obo/mondo/patterns/squamous_cell_carcinoma.yaml

exactMatch

http://linkedlifedata.com/resource/umls/id/C0585362

http://purl.obolibrary.org/obo/DOID_0050866

http://www.orpha.net/ORDO/Orphanet_502363

http://purl.obolibrary.org/obo/NCIT_C4833

http://identifiers.org/medgen/108436

http://identifiers.org/snomedct/307502000

has related synonym

OCSC

oral squamous cell carcinoma

id

MONDO:0004958

seeAlso

https://rarediseases.info.nih.gov/diseases/7263/oral-squamous-cell-carcinoma