A large, well differentiated squamous cell carcinoma with a cauliflower-like appearance, characterized by the presence of an exophytic and endophytic growth pattern. Morphologically, there is papillomatosis and acanthosis present, however cytologically the neoplastic squamous cells have a benign appearance. Dysplastic changes are minimal. It does not respond to conservative treatment and it is regarded by many authors as an intermediate lesion between condyloma acuminatum and squamous cell carcinoma. [ NCIT:C7470 ]
Synonyms: anal verrucous carcinoma anal Buschke-Lowenstein tumor anal Buschke-Lowenstein tumour anal giant (malignant) condyloma
Term information
- NCIT:C7470 (MONDO:equivalentTo)
- MEDGEN:231066 (MONDO:equivalentTo)
- UMLS:C1332278 (MONDO:equivalentTo)
- DOID:7175 (MONDO:equivalentTo)
gard_rare, rare
http://linkedlifedata.com/resource/umls/id/C1332278
http://identifiers.org/medgen/231066
http://purl.obolibrary.org/obo/NCIT_C7470
http://purl.obolibrary.org/obo/DOID_7175
http://purl.obolibrary.org/obo/mondo/sparql/qc/general/qc-single-child.sparql