A dome-shaped, rapidly growing skin lesion composed of well differentiated squamous cells. It represents a proliferation of the infundibular epithelium of the hair follicle and its morphologic distinction from a well differentiated carcinoma may be difficult or impossible. Keratoacanthomas affect males more frequently than females and the majority tend to regress spontaneously. It has been suggested that keratoacanthoma represents a distinct subtype of squamous cell carcinoma of the skin. [ NCIT:C3146 ]
Term information
- MEDGEN:5954 (MONDO:equivalentTo)
- ICDO:8071/1 (NCIT:C3146)
- MESH:D007636 (MONDO:equivalentTo)
- DOID:3149 (MONDO:equivalentTo)
- SCTID:254662007 (MONDO:equivalentTo)
- NCIT:C3146 (MONDO:exact-label-match)
- UMLS:C0022572 (MONDO:equivalentTo)
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Clinically and histologically, it may be confused with a de novo highly malignant squamous cell carcinoma (SCC). However, KA may be viewed as an abortive cancer that only rarely progresses into an aggressive SCC - PMID:8277007.
http://purl.obolibrary.org/obo/DOID_3149
http://linkedlifedata.com/resource/umls/id/C0022572
http://identifiers.org/mesh/D007636
http://purl.obolibrary.org/obo/NCIT_C3146
http://identifiers.org/snomedct/254662007
http://identifiers.org/medgen/5954