The dense region demarcating the thymus medulla from the surrounding cortex that is characterized by numerous blood vessels (predominantly arterioles) with some perivascular connective tissue, mature and immature T lymphocytes, dendritic cells, variable numbers of perivascular B-lymphocytes and plasma cells; site of entry of bone marrow stem cells and exit of mature, functional T cells. [ MP:0009543 ]
Synonyms: thymic cortico-medullary boundary thymus CMZ thymus cortico-medullary boundary thymic corticomedullary zone thymus corticomedullary junction thymus corticomedullary zone thymic corticomedullary junction thymic corticomedullary boundary
Term information
Term relations
- anatomical junction and overlaps some cortex of thymus and overlaps some medulla of thymus
- mixed endoderm/mesoderm-derived structure
- anatomical junction
- part of some thymus lobule
- overlaps some cortex of thymus
- has part some dendritic cell
- contributes to morphology of some thymus lobule
- has part some lymphocyte
- overlaps some medulla of thymus
- has part some arteriole
- has part some perivascular macrophage