A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. [ MP:0009846 ]
Synonyms: NC
Term information
- CALOHA:TS-0676
- SCTID:361462002
- Wikipedia:Neural_crest
- neuronames:1366
- VHOG:0000057
- ZFA:0000045
- FMA:86666
- XAO:0000048
- NCIT:C34222
- EMAPA:32737
- GAID:1310
- BTO:0001764
- MAT:0000066
- MIAA:0000066
- AAO:0010578
- MESH:D009432
- EHDAA2:0004419
uberon_slim, pheno_slim, vertebrate_core
Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995), slug (Nieto et al., 1994), AP-2 (Zhang et al., 1996; Schorle et al., 1996), and Wnt-1/3a (Ikeya et al., 1997) are expressed in the dorsal most region of the neural tube, and have been shown to be involved in the generation of neural crest cells.
Term relations
- ectoderm-derived structure
- germ layer / neural crest
- structure with developmental contribution from neural crest
- part of some neurectoderm
- composed primarily of some migratory neural crest cell
- develops from some neural fold
- existence starts during some neurula stage
- develops from some neural plate