In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. [ http://en.wikipedia.org/wiki/Pronephros http://amigo.geneontology.org/amigo/term/GO:0048793 ]
Synonyms: pronephric kidney
Term information
- TAO:0000151
- ZFA:0000151
- EHDAA:1017
- SCTID:308804007
- MIAA:0000117
- FMA:72170
- BTO:0001541
- EFO:0000927
- EMAPA:16579
- AAO:0011089
- MAT:0000117
- Wikipedia:Pronephros
- NCIT:C34280
- XAO:0002000
- VHOG:0000037
- EHDAA2:0001570
uberon_slim, efo_slim, organ_slim
Once the more complex mesonephros forms the pronephros undergoes apoptosis in amphibians. In fishes the nephron degenerates but the organ remains and becomes a component of the immune system[Wikipedia:Pronephros]. // TODO - check developmental relationships. Note that we previously include the ZFA/XAO terms under the more specific 'pronephric kidney', but these are now merged. TODO GCI: relationship: capable_of GO:0030104