Pathological deposition of calcium salts in one or more arteries. [ http://www.ncbi.nlm.nih.gov/pubmed/18519861 https://orcid.org/0000-0002-0736-9199 ]
Term information
- UMLS:C1168153
Most individuals aged over 60 years have progressively enlarging deposits of calcium mineral in their major arteries. This vascular calcification reduces aortic and arterial elastance, which impairs cardiovascular hemodynamics, resulting in substantial morbidity and mortality in the form of hypertension, aortic stenosis, cardiac hypertrophy, myocardial and lower-limb ischemia, congestive heart failure, and compromised structural integrity.The severity and extent of mineralization reflect atherosclerotic plaque burden and strongly and independently predict cardiovascular morbidity and mortality. (From PMID:18519861).
Term relations
- has part some (
calcified and
characteristic of some artery and
has modifier some abnormal)