Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers. [ http://www.ncbi.nlm.nih.gov/pubmed/17922016 GOC:tfm http://www.ncbi.nlm.nih.gov/pubmed/16551251 http://purl.obolibrary.org/obo/go/references/0000031 http://www.ncbi.nlm.nih.gov/pubmed/19286519 GOC:amm ]
Synonyms: pro-DCs common dendritic precursor CDP
Term information
cellxgene_subset
Surface markers are for mouse cells. Originally described in the dendritic cell ontology (DC_CL:0000041) CDP are reportedly CD2-negative, CD3-negative, CD4-negative, CD5-negative, CD8a-negative, CD11c-positive, CD14-negative, CD19-negative, CD20-negative, CD56-negative, B220-negative, Ly6g-negative, MHCII-positive, and Ter119-negative. (PMID:19243617).
Term relations
- hematopoietic lineage restricted progenitor cell and lacks_plasma_membrane_part some CD19 molecule and lacks_plasma_membrane_part some CD4 molecule and lacks_plasma_membrane_part some integrin alpha-M and lacks_plasma_membrane_part some CD3 epsilon and lacks_plasma_membrane_part some neural cell adhesion molecule 1 and lacks_plasma_membrane_part some CD2 molecule and lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain and lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1 and lacks_plasma_membrane_part some T-cell surface glycoprotein CD5 and lacks_plasma_membrane_part some CD14 molecule and lacks_plasma_membrane_part some lymphocyte antigen 6G and lacks_plasma_membrane_part some lymphocyte antigen 76 (mouse) and has plasma membrane part some receptor-type tyrosine-protein kinase FLT3 and has plasma membrane part some macrophage colony-stimulating factor 1 receptor and has low plasma membrane amount some mast/stem cell growth factor receptor
- hematopoietic lineage restricted progenitor cell
- CD115-positive monocyte OR common dendritic progenitor
- myeloid cell
- lacks_plasma_membrane_part some lymphocyte antigen 6G
- lacks_plasma_membrane_part some integrin alpha-M
- lacks_plasma_membrane_part some lymphocyte antigen 76 (mouse)
- has low plasma membrane amount some mast/stem cell growth factor receptor
- has plasma membrane part some receptor-type tyrosine-protein kinase FLT3
- lacks_plasma_membrane_part some CD3 epsilon
- lacks_plasma_membrane_part some CD2 molecule
- has plasma membrane part some macrophage colony-stimulating factor 1 receptor
- lacks_plasma_membrane_part some CD14 molecule
- lacks_plasma_membrane_part some T-cell surface glycoprotein CD5
- lacks_plasma_membrane_part some T-cell surface glycoprotein CD8 alpha chain
- develops from some macrophage dendritic cell progenitor
- lacks_plasma_membrane_part some CD19 molecule
- lacks_plasma_membrane_part some neural cell adhesion molecule 1
- lacks_plasma_membrane_part some CD4 molecule
- lacks_plasma_membrane_part some membrane-spanning 4-domains subfamily A member 1