A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface. [ http://purl.obolibrary.org/obo/go/references/0000031 GOC:dsd http://www.ncbi.nlm.nih.gov/pubmed/20933013 http://www.ncbi.nlm.nih.gov/pubmed/9295047 GOC:add GOC:rhs https://www.worldcat.org/search?q=bn%3A0781765196 ]
Synonyms: class switched memory B-cell class switched memory B-lymphocyte class switched memory B lymphocyte
Term information
cellxgene_subset, human_reference_atlas
Per DSD: Class switched memory B cells are also reportedly CD48-positive, CD229-positive, and CD352-positive.
Term relations
- memory B cell and lacks_plasma_membrane_part some IgM immunoglobulin complex and has plasma membrane part some CD27 molecule and output of some isotype switching