A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type. [ GOC:dsd http://www.ncbi.nlm.nih.gov/pubmed/8006591 http://www.ncbi.nlm.nih.gov/pubmed/18432934 GOC:msz http://purl.obolibrary.org/obo/go/references/0000031 ]
Synonyms: Bm3 B-lymphocyte Bm3 B-cell Bm3 B lymphocyte
Term information
Bm3 B cells are also reportedly CD10-positive, CD23-negative, CD39-negative, CD44-negative, CD71-positive, and CD77-positive.
Term relations
- germinal center B cell and lacks_plasma_membrane_part some IgD immunoglobulin complex and has plasma membrane part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 and has plasma membrane part some lactosylceramide 4-alpha-galactosyltransferase and capable of some somatic hypermutation of immunoglobulin genes
- germinal center B cell
- capable of some somatic hypermutation of immunoglobulin genes
- has plasma membrane part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- lacks_plasma_membrane_part some IgD immunoglobulin complex
- develops from some Bm2' B cell
- has plasma membrane part some lactosylceramide 4-alpha-galactosyltransferase