A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes. [ http://www.ncbi.nlm.nih.gov/pubmed/9785673 http://www.ncbi.nlm.nih.gov/pubmed/18432934 http://www.ncbi.nlm.nih.gov/pubmed/16551251 GOC:dsd GOC:tfm http://purl.obolibrary.org/obo/go/references/0000031 GOC:rhs ]
Synonyms: small pre-BII cell
Term information
cellxgene_subset
Small pre-B-II cells are also reportedly CD10-positive, CD19-positive, CD34-negative, CD79a-positive, CD127-negative, TdT-negative, Vpre-B-negative, sIgM-negative, and sIgD-negative. Transcription factors: PU.1-positive, Ikaros-positive, E2A-positive, and PAX5-positive.
Term relations
- pre-B-II cell and has part some V(D)J recombination-activating protein 1 and has part some V(D)J recombination-activating protein 2 and lacks_plasma_membrane_part some B cell receptor complex and lacks_plasma_membrane_part some pre-B cell receptor complex and participates in some immunoglobulin light chain V-J recombination
- pre-B-II cell
- lacks_plasma_membrane_part some B cell receptor complex
- lacks_plasma_membrane_part some pre-B cell receptor complex
- has part some V(D)J recombination-activating protein 1
- participates in some immunoglobulin light chain V-J recombination
- has part some V(D)J recombination-activating protein 2